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依克立達

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Elacridar (Synonyms: GF120918; GW0918; GG918; GW120918)

產品編號：CL1400 CAS No.：143664-11-3 MDLNo：MFCD00912604 分子式：C34H33N3O5 分子量：563.64
規格 庫存 目錄價 會員專享價 數量
2 mg In-stock ￥226.00 登錄后可見
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5 mg In-stock ￥366.00 登錄后可見
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10 mg In-stock ￥538.00 登錄后可見
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基本信息
英文名稱 Elacridar (Synonyms: GF120918; GW0918; GG918; GW120918)
中文名稱依克立達
CAS號143664-11-3
分子式C34H33N3O5
分子量563.64
MDLMFCD00912604
外觀Light yellow to brown powder
儲存條件Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
產品詳情

Elacridar is an orally active P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) inhibitor. Elacridar can be used to examine the influence of efflux transporters on agent distribution to brain and the research of cancer.

GF120918 (Elacridar) is a very potent inhibitor of the ABC transporters MDR-1 (P-gp) and BCRP. GF120918 increases the bioavailability of cytotoxic anti-tumor drugs, and also leads to increased levels of anti-HIV drugs in the brain and CNS.

GF120918 (Elacridar) is an inhibitor of MDR-1 (P-gp).

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Elacridar | GF120918 |  GW0918 | GG918 | GW120918 | ABC transporters MDR-1 (P-gp) inhibitor |  N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide

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