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康普瑞汀磷酸二鈉

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Fosbretabulin Disodium (Synonyms:CA 4DP; CA 4P; Combretastatin A4 Disodium Phosphate(CA4P))

產品編號：CL2386 CAS No.：168555-66-6 MDLNo： 分子式：C18H19PO8Na2 分子量：440.29
規格 庫存 目錄價 會員專享價 數量
10 mg In-stock ￥700.00 登錄后可見
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20 mg In-stock ￥1120.00 登錄后可見
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50 mg In-stock ￥2200.00 登錄后可見
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基本信息
英文名稱 Fosbretabulin Disodium (Synonyms:CA 4DP; CA 4P; Combretastatin A4 Disodium Phosphate(CA4P))
中文名稱康普瑞汀磷酸二鈉
CAS號168555-66-6
分子式C18H19PO8Na2
分子量440.29
外觀White powder
儲存條件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產品詳情

Fosbretabulin (Combretastatin A4 Phosphate, CA4P, CA 4DP) Disodium is the water-soluble prodrug of Combretastatin A4 (CA4), which is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM in a cell-free assay. Fosbretabulin Disodium inhibits the polymerization of tubulin with IC50 of 2.4 μM, and also disrupts tumor vasculature. Fosbretabulin disodium induces mitotic arrest and apoptosis in endothelial cells. Phase 3.
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