Romiplostim(AMG531,Romiplate) is a thrombopoietin receptor agonist (TPO-RA), a TPO analogue, and a Fc-peptide fusion protein (peptide body).
Romiplostim is a fusion protein analogue of TPO (thrombopoietin protein) Fc peptide, and is a peptide-body molecule. Romiplostim increases platelet production by activating the thrombopoietin receptor TPO receptor. The peptidosome molecule has two identical single-stranded subunits, each consisting of 269 amino acid residues.
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