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高三尖杉酯堿

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Homoharringtonine (Synonyms: CGX-635; Omacetaxine mepesuccinate; HHT; Myelostat; NSC 141633)

產(chǎn)品編號(hào)：HL1109 CAS No.：26833-87-4 MDLNo：MFCD05618221 分子式：C29H39NO9 分子量：545.62
規(guī)格 庫存 目錄價(jià) 會(huì)員專享價(jià) 數(shù)量
5 mg 3-5 days ￥406.00 登錄后可見
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10 mg 3-5 days ￥668.00 登錄后可見
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25 mg 3-5 days ￥1088.00 登錄后可見
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50 mg 3-5 days ￥1766.00 登錄后可見
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基本信息
英文名稱 Homoharringtonine (Synonyms: CGX-635; Omacetaxine mepesuccinate; HHT; Myelostat; NSC 141633)
中文名稱高三尖杉酯堿
CAS號(hào)26833-87-4
分子式C29H39NO9
分子量545.62
MDLMFCD05618221
外觀Off-white to yellow powder
儲(chǔ)存條件 4°C, protect from light
產(chǎn)品詳情

Homoharringtonine (Omacetaxine mepesuccinate; HHT) is a cytotoxic alkaloid derived from the Cephalotaxus tree, known for its significant antitumor properties. HHT acts primarily by inhibiting translation elongation, which disrupts protein synthesis crucial for cancer cell survival. This mechanism leads to the rapid degradation of several short-lived proteins, including Mcl-1 and c-Myc, triggering apoptosis in various cancer types, particularly in hematological malignancies such as acute myeloid leukemia (AML).
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